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Extensive CYP 2D6 metabolizers convert risperidone rapidly into 9-hydroxyrisperidone, whereas poor CYP 2D6 metabolizers convert it much more slowly.

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With regard to treatment in patients suffering from sexual dysfunction, sildenafil was associated with significantly more erections sufficient for penetration as compared to a placebo.

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The primary hypothesis was that in the first 16 weeks of phase B, the risk of relapse would be lower among patients who continued risperidone therapy (groups 1 and 2) than among those who received placebo (group 3).

Acute increases, of two- to tenfold, have also been observed after single parenteral or oral doses of phenothiazines.

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Firstly, this review includes initial data published at international congresses that are not yet subject to peer review, but nonetheless provide clinicians with early and important information.

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Do not drink alcohol during your treatment with risperidone extended-release injection.

Most people on antipsychotics get side effects.

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ADRs do not include therapeutic failures, poisoning, accidental or intentional overdoses.

Fortunately for me, the was the first mood stabilizer they tried on me, and it started working within the first week (I take 1500mg of it).

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Brand names include Risperdal, Risperdal Consta, Risperdal M-Tab, Risperdal Quicklets.

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Risperidone is a safe and effective new antipsychotic that has a high binding affinity for both serotonin and dopamine receptors.

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The concept of health-related quality of life (HRQoL) has not been a treatment outcome focused upon in studies until the last few years.

The goals of treatment of these patients include reducing symptoms and potentially improving long-term treatment outcomes.

More children have been diagnosed this year than those with diabetes, AIDS, etc.

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Competing interests: All authors have completed the ICMJE uniform disclosure form at (available on request from the corresponding author) and declare: no support from any organisation for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work in the previous three years; no other relationships or activities that could appear to have influenced the submitted work.

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The rare but potentially life-threatening cardiac events caused by atypical antipsychotics, which are threshold-types of events triggered by excessive plasma levels of the drug, should be an even less significant risk with the injectable form than it is with risperidone tablets.

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Several studies have also reported that patients considered symptomatically stable on oral risperidone can be safely switched to long-acting risperidone (; ), thereby contradicting the perception of some clinicians and patients that adverse events are more common with long-acting than with oral formulations.

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In addition, assessments on the Strauss-Carpenter Level of Functioning Scale (LOF) indicated that patients had a greater frequency of social contacts, increased quality of relationships, and a improved overall level of function during maintenance treatment with long-acting risperidone.

Psychotic symptoms are present in at least 25 percent of mildly demented patients with Alzheimer's disease and in 50 percent of patients with advanced Alzheimer's disease.

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Risperidone was effective and well tolerated for the treatment of tantrums, aggression, or self-injurious behavior in children with autistic disorder.

When initiating an enzyme inducer while receiving injectable risperidone, monitor patients closely for the first 4 to 8 weeks for possible dose adjustment (increased injection dose or supplementation with oral risperidone).

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Major effects in these patients included lethargy (10), coma (1), seizure (1), tachycardia (7), bradycardia (1), hypotension (4), and a syndrome of muscle spasms, diaphoresis, and fever.

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An antipsychotic is recommended in patients who are displaying psychotic features.

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Relapses increase refractoriness to future treatment leading to more frequent and prolonged hospitalization, and contribute significantly to the economic burden of schizophrenia.

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He was given trihexiphenidyl and the escitalopram was continued.

The findings of this study are highly clinically relevant and have immediate transformational value for the management of bipolar disorder.

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However, since both dopamine and norepinephrine both can play major roles with regards to ADHD and the symptoms of the disorder, this enzymatic conversion process is still of importance.

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After randomization, there were no significant differences between groups with respect to VA service use () or non-VA service use (Table 4 in the ), including the number of hospital days.

The efficacy of Risperidone in the treatment of schizophrenia in adolescents aged 13 to 17 years was demonstrated in two short-term (6 and 8 weeks), double-blind controlled trials.

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With the top-level data publicly available today it is very difficult to differentiate any potential direct pharmacokinetic benefit which risperidone LAI might have over the tablet form, beyond what results from the LAI form ensuring drug levels in plasma (and by implication, also in the brain) that consistently remain in the therapeutic range.

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Overall, the clinical use of Formulations A, B, C, or D will eliminate the need for combination oral therapy and reduce time to achieve steady state, with a smaller washout period upon cessation of therapy.

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When researching the stories and studies on tyrosine supplementation for ADHD, the one thing that continuously caught my attention was the degree of discord between the studies on tyrosine supplementation for ADHD (most of which showed no significant improvement) and the number of clinicians who prescribed it (and individuals who reported benefits from tyrosine).

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The adverse events occurred due to the administration of incorrect medication and included confusion, lethargy, ataxia, hallucinations, tiredness, dizziness, tingling, numbness and altered mental status.

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Successive relapses can reduce the degree and duration of the next remission, worsen disability, and increase refractoriness to future treatment.

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